Carotenoids obi
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   CA00043  Lycopene
  • Antifungal activity against C. albicans by aressting their cell cycle (Ref.482).

    •    CA00513  Fucoxanthinol
  • Cell cycle arrest during G1 phase, up-regulation of PARP cleavage, caspase-3, -8 and -9 cleavage, silencing of NF-κB, AP-1and PI3K/Akt pathways and proteins proteasome degradation (Ref.493).

    •    CA01219  Apo-12'-lycopenal
  • Reduce the proliferation of prostate cancer cells by inhibiting normal cell cycle progression. (Ref.695)

    •    CA00795  10'-Apolycopen-10'-oic acid
  • Induce cell cycle arrest in cancer cells (Ref.415).

    •    CA00844  β-Apo-12'-carotenal
  • Induce cell cycle arrest in cancer cells (Ref.415).

  • Ref.482 : Sung Woo Sang, In-Seon-Lee, and Dong Gun Lee, J. Microbiol. Biotechnol. (2007), 17(11), 1797-1804, "Damage to the Cytoplasmic Membrane and Cell Death Caused by Lycopene in Candida albicans".
  • Ref.493 : Anne-Laure Gagez, ValĂ©rie Thiery, Virginie Pasquet, Jean-Paul Cadoret, and Laurent Picot, Current Bioactive Compounds 2012, 8, 000-000, "Epoxycarotenoids and Cancer. Review".
  • Ref.695 : Ford NA, Elsen AC, Zuniga K, Lindshield BL, Erdman JW Jr., Nutr Cancer. 2011;63(2):256-63. "Lycopene and apo-12'-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cells.", doi: 10.1080/01635581.2011.523494..
  • Ref.415 : Takuji Tanaka, Masahito Shnimizu, and Hisataka Moriwaki, Molecules 2012, 17, 3202-3242; doi:10.3390/molecules17033202, "Cancer Chemoprevention by Carotenoids".
    • Since June 15, 2015 by Junko Yabuzaki.