Activate transcription of the retinoic acid receptors (Ref.423).
Ref.423 : CHARLES C. ACHKAR, FADILA DERGUINI, BRUCE BLUMBERG, ALEXANDER LANGSTON, ARTHUR A. LEVINTII, JEFFREY SPECKS, RONALD M. EVANS, JACK BOLADO, JR., KoJi NAKANISHI, JOCHEN BUCK, AND LORRAINE J. GUDAS, Proc. Natl. Acad. Sci. USA Vol. 93, pp. 4879-4884, May 1996 Pharmacology, "4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors".