Carotenoids obi
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   CA01082  Crocusatin H
   Strong tyrosinase inhibitory activity. (Ref.485).

   CA00898  Crocin
   Strong tyrosinase inhibitory activity (Ref.485).

   CA00901  Crocin 3
   Strong tyrosinase inhibitory activity (Ref.485).

   CA00894  Bixin
   Anticarcinogenic activity - inhibit tyrosinase activity in melanoma cells in vitro (Ref.481).

   CA00893  Norbixin
   Anticarcinogenic activity - inhibit tyrosinase activity in melanoma cells in vitro (Ref.481).

  • Ref.485 : Li CY, Wu TS, Journal of Natural Products [2002, 65(10):1452-1456], DOI: 10.1021/np020188v, "Constituents of the stigmas of Crocus sativus and their tyrosinase inhibitory activity.".
  • Ref.481 : Anantharaman A, Hemachandran H, Priya RR, Sankari M, Gopalakrishnan M, Palanisami N, Siva R., J Biosci Bioeng. 2015 Jul 14. pii: S1389-1723(15)00200-5. doi: 10.1016/j.jbiosc.2015.05.007., PMID: 26187443, "Inhibitory effect of apocarotenoids on the activity of tyrosinase: Multi-spectroscopic and docking studies".
  • Since June 15, 2015 by Junko Yabuzaki.