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☀ Pathway reconstructed carotenoids:       [  Search similar carotenogenesis pathway constructing organisms  ]  
  1. CA00264 (Flexixanthin)
  2. CA00266 (4-Ketomyxol)
☀ Pathway unconstructed carotenoids: None
☀ Lycopene biosynthesis type: Bacterial type (Ref.690)

  ☀ CA00043 (Lycopene) biosynthesis pathway

   Path: CA00189 (Prephytoene pyrophosphate (diphosphate)) -> CA00060 (Phytoene) -> CA00058 ((all-E)-Phytofluene) -> CA00051 (ζ-Carotene) -> CA00047 (Neurosporene) -> CA00043 (Lycopene)

   See: CB000005 (Bacterial and fungal pathway: CA00189 -> CA00060 -> CA00058 -> CA00051 -> CA00047 -> CA00043)

   Necessary enzymes for those reactions in theory: CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (CR00277: CA00189 -> CA00060) --> Crtlb(1.3.99.28), CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.99.29), Crtla(1.3.99.29) (CR00389: CA00060 -> CA00058) --> CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.5.5, 1.3.99.29), Crtla(1.3.99.29) (CR00115: CA00058 -> CA00051) --> PDS(1.3.5.5, 1.3.99.29), CitPDS1(1.3.5.5), BoPDS(1.3.5.5), CrtI(1.3.5.6, 1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00136: CA00051 -> CA00047) --> CrtI(1.3.5.6, 1.3.99.30, 1.3.99.31), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6), Crtlb(1.3.99.26) (CR00132: CA00047 -> CA00043)




  ☀ CA00264 (Flexixanthin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00202 (1'-Hydroxy-γ-carotene) -> CA00217 (1'-Hydroxytorulene) -> CA00205 (Saproxanthin) -> CA00264 (Flexixanthin)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000024 (Knwon path in purple bacterium: CA00191 -> CA00202), CB000024 (Knwon path in purple bacterium: CA00202 -> CA00217), CB000153 (CA00217 -> CA00205), similar to CB000026: CA00228 -> CA00266 (proposed reaction: CA00205 -> CA00264)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtC (CR00344: CA00191 -> CA00202) --> unknown (CR00113: CA00202 -> CA00217) --> unknown (CA00217 -> CA00205) --> unknown (CA00205 -> CA00264)




  ☀ CA00266 (4-Ketomyxol) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00228 (Myxol) -> CA00266 (4-Ketomyxol)

   See: CB000027 (Knwon path in Anabaena (cyanobacterium): CA00043 -> CA00191 -> CA00228 -> CA00266)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> unknown (CA00191 -> CA00228) --> CrtW (CR00248: CA00228 -> CA00266)



Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428
Since June 15th, 2015 by Junko Yabuzaki.