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Entry
CR00259                                                            
Classification
Name
alcohol dehydrogenase [NAD(P)+]; alcohol:NAD(P)+ oxidoreductase; all-trans-retinol dehydrogenase (NAD+); all-trans retinol:NAD+ oxidoreductase
Definiton
All-trans-retinal + NADPH + H+ + O2 = All-trans-retinol + NADP+ + H2O
Substrate
CA00807 Retinal (15-al, 15-apo, beta)
Product
CA01031 Vitamin A (15-OH, 15-apo, beta)
Comment

Structure change

Chemical Fingerprint Changes 
Chemical Fingerprint Changes 
(improved)
Chemical Fingerprint Changes 
(improved ver.2)
EC number
1.1.1.71; 1.1.1.105
Protein Name
AtRDH
Organism(s) in references
Vertebrates
Data sources/References
  • Ref.579 : Alexander R. Moise, Johannes von Lintig and Krzysztof Palczewski, TRENDS in Plant Science Vol.10 No.4 April 2005, "Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids"
  • Ref.583 : Mata NL, Radu RA, Clemmons RC, Travis GH., Neuron. 2002 Sep 26;36(1):69-80., PMID: 12367507 PMCID: PMC2851622, "Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight."
    • Links to other DB
    KEGG ENZYME: 1.1.1.71, 1.1.1.105
    BRENDA: 1.1.1.71, 1.1.1.105
    IUBMB: 1.1.1.71, 1.1.1.105

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