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CA00043  Lycopene Anti-inflammation (Ref.408). Anti-inflammatory effects of lycopene may help alleviate neuropsychiatric diseases such as post-traumatic stress disorder and depression (Ref.782).    CA00502  (3S,3'S)-Astaxanthin Attenuates depressive-like behaviors in rodents by preventing neuroinflammation and regulating survival pathways including PI3K/Akt. (Ref.782)    CA00519  Fucoxanthin Anti-inflammatory activity (Ref.512, Ref.513).    CA00597  Lutein Inhibits NF-KB dependent inflammatory gene expressions (Ref.460).    CA00746  Capsanthin 3,6-epoxide Strong anti-inflammatory activity (Ref.581).    CA01225  Loliolide Anti-inflammatory and antiaging activity (Ref.768). Ref.408 : Jonathan R Mein, Fuzhi Lian, Xiang-Dong Wang, Nutr Rev. 2008 Dec;66(12):667-83. doi: 10.1111/j.1753-4887.2008.00120.x., PMID: 19019036, "Biological activity of lycopene metabolites: implications for cancer prevention". Ref.782 : Han-A Park et al., Molecules 2020, 25, 3453, “Anti-Apoptotic Effects of Carotenoids in Neurodegeneration”, doi:10.3390/molecules25153453. Ref.512 : K.-N. Kim, S.-J. Heo, W.-J. Yoon et al., “Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-𝜅B and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages,” European Journal of Pharmacology, vol. 649, no.1–3, pp. 369–375, 2010. Ref.513 : S. Sakai, T. Sugawara, K. Matsubara, and T. Hirata, “Inhibitory effect of carotenoids on the degranulation of mast cells via suppression of antigen-induced aggregation of high affinity IgE receptors,” The Journal of Biological Chemistry, vol. 284, no. 41, pp. 28172–28179, 2009.. Ref.460 : Ji-Hee Kim, Hee-Jun Na, Chun-Ki Kim, Ji-Yoon Kim, Kwon-Soo Ha, Hansoo Lee, Hun-Taeg Chung, Ho Jeong Kwon, Young-Guen Kwon, Young-Myeong Kim, Free Radical Biology & Medicine 45 (2008) 885–896, "The non-provitamin A carotenoid, lutein, inhibits NF-κB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-κB-inducing kinase pathways: Role of H2O2 in NF-κB activation". Ref.581 : Murakami, A. Nakashima, M. Koshiba, T. Maoka, T. Nishino, H. Yano, M. Sumida, T. Kim, O.K. Koshimizu, K. Ohigashi, H., Cancer letters, 2000, 149, 115-123., “Modifying effects of carotenoids on superoxide and nitric oxide generation from stimulated leukocytes.” . Ref.768 : Sang Hee Park et al., Int. J. Mol. Sci. 2019, 20, 651; doi:10.3390/ijms20030651, “Loliolide Presents Antiapoptosis and Antiscratching Effects in Human Keratinocytes”.

Since June 15, 2015 by Junko Yabuzaki.