Carotenoids obi
All carotenoids     All organisms     All pathways     All reactions     Feedback CarotenoidsDB: Antiproliferative acivities
welcome
  [   About  |   Help  |   Search carotenoid entry  |   Search organism entry  |   Search similar carotenoids  |   Predict biological activities of a carotenoid  ]


   CA00441  (8'R)-Luteoxanthin
  • Reverse MDR in MCF-7 cells and potentiate epirubicin antiproliferative activity in L5178 (Ref.492).

  •    CA00442  (8'S)-Luteoxanthin
  • Reverse MDR in MCF-7 cells and potentiate epirubicin antiproliferative activity in L5178 (Ref.492).

  •    CA00416  Violaxanthin
  • Anticarcinogenic activity - antiproliferative alone, early apoptosis effect in MCF-7 cell (Ref.493).

  •    CA01083  Dinochrome A
  • Antiproliferative activity on HeLa cells at the concentration of 25 g.mL-1 which inhibited 72% growth after 4h (Ref.494).

  •    CA01084  Dinochrome B
  • Antiproliferative activity on HeLa cells at the concentration of 25 g.mL-1 (Ref.494).

  •    CA00513  Fucoxanthinol
  • Antiproliferative activity in various cancer cells by downregulating anti-apoptotic proteins and cell cycly regulators: Bcl2, Bcl-xL, XIAP, survivin, p-caspase-9, cyclin D1, cyclin D2, CDK4, CDK6, c-myc and ppRb (Ref.493).

  •    CA00519  Fucoxanthin
  • Antiproliferative, and chemopreventive activity (Ref.493).

  •    CA00413  Peridininol 5,8-furanooxide
  • Anticarcinogenic activity - significant growth-inhibitory activity toward cancer cells - antiproliferative activity (Ref.568).

  •    CA00428  Peridinine 5,8-furanoside
  • Anticarcinogenic activity - significant growth-inhibitory activity toward cancer cells - antiproliferative activity (Ref.568).

  •    CA01088  Nor-peridinin2
  • Anticarcinogenic activity - moderate antiproliferative activity against cancer cell lines such as human BSY-1 (breast), SNB-75 (central nervous system), HCT-116 (colon), NCI-H522 and DMS114(lung), and MKN7 (stomach) (Ref.493).

  •    CA00579  Peridinin
  • Anticarcinogenic activity - moderate antiproliferative, moderate cytotoxicity in HeLa cell by activating caspases-8 and -9 (Ref.493, Ref.494).

  • Ref.492 : Péter Molnár, József Deli, Toru Tanaka,Yoshiyuki Kann, Satoru Tani, Nóra Gyémánt, Joseph Molnár ,and Masami Kawase, Phytotherapy Research, Volume 24, Issue 5, pages 644–648, May 2010, “Carotenoids with anti-Helicobacter pylori activity from Golden deliciousapple”.
  • Ref.493 : Anne-Laure Gagez, Valérie Thiery, Virginie Pasquet, Jean-Paul Cadoret, and Laurent Picot, Current Bioactive Compounds 2012, 8, 000-000, "Epoxycarotenoids and Cancer. Review".
  • Ref.494 : Takashi MAOKA, Miyuki TSUSHIMA, and Hoyoku NISHINO, Chem. Pharm. Bull. 50(12) 1630—1633 (2002), "Isolation and Characterization of Dinochrome A and B, Anti-carcinogenic Active Carotenoids from the Fresh Water Red Tide Peridinium bipes".
  • Ref.568 : Suzuki M, Watanabe K, Fujiwara S, Kurasawa T, Wakabayashi T, Tsuzuki M, et al., Chem Phrm Bull 2003;51:724–7. "Isolation of peridinin-related norcarotenoids with cell growth-inhibitory activity from the cultured dinoflagellate of Symbiodinium sp., a symbiont of the Okinawan soft coral Clavularia virdis, and analysis of fatty acid of the dinoflagellate.".
  • Since June 15, 2015 by Junko Yabuzaki.