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CarotenoidsDB:
Myxococcus fulvus
carotenoids (Bacterial) reconstructed pathways in theory
(Deltaproteobacteria: halotolerant marine myxobacterium)
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Click here to see the carotenoid profile of Myxococcus fulvus
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Pathway reconstructed carotenoids:
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CA00042 (3,4-Dehydrolycopene)
CA00183 (4,4'-Diketolycopene)
CA00281 (1',2'-Dihydro-4,2'-diketotorulene)
CA00280 (4,4'-Diketo-γ-carotene)
CA00271 (1',2'-Dihydroxy-4-ketotorulene)
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Pathway unconstructed carotenoids:
None
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Lycopene biosynthesis type:
Bacterial type (Ref.690)
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CA00043 (Lycopene)
biosynthesis pathway
Path:
CA00189
(Prephytoene pyrophosphate (diphosphate))
->
CA00060
(Phytoene)
->
CA00058
((all-E)-Phytofluene)
->
CA00051
(ζ-Carotene)
->
CA00047
(Neurosporene)
->
CA00043
(Lycopene)
See:
CB000005
(Bacterial and fungal pathway: CA00189 -> CA00060 -> CA00058 -> CA00051 -> CA00047 -> CA00043)
Necessary enzymes for those reactions in theory:
CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (
CR00277
: CA00189 -> CA00060) --> Crtlb(1.3.99.28), CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.99.29), Crtla(1.3.99.29) (
CR00389
: CA00060 -> CA00058) --> CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.5.5, 1.3.99.29), Crtla(1.3.99.29) (
CR00115
: CA00058 -> CA00051) --> PDS(1.3.5.5, 1.3.99.29), CitPDS1(1.3.5.5), BoPDS(1.3.5.5), CrtI(1.3.5.6, 1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (
CR00136
: CA00051 -> CA00047) --> CrtI(1.3.5.6, 1.3.99.30, 1.3.99.31), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6), Crtlb(1.3.99.26) (
CR00132
: CA00047 -> CA00043)
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CA00042 (3,4-Dehydrolycopene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00042
(3,4-Dehydrolycopene)
See:
CB000078
(Knwon path in mold: CA00043 -> CA00042)
Necessary enzymes for those reactions in theory:
CrtI (
CR00119
: CA00043 -> CA00042)
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CA00183 (4,4'-Diketolycopene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00183
(4,4'-Diketolycopene)
See:
Proposed reaction (CA00043 -> CA00183)
Necessary enzymes for those reactions in theory:
unknown (CA00043 -> CA00183)
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CA00281 (1',2'-Dihydro-4,2'-diketotorulene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00042
(3,4-Dehydrolycopene)
->
CA00190
(Torulene)
->
CA00255
(4-Ketotorulene)
->
CA00281
(1',2'-Dihydro-4,2'-diketotorulene)
See:
CB000077
(Knwon path in mold: CA00043 -> CA00042),
CB000078
(Knwon path in mold: CA00042 -> CA00190), similar to
CB000026: CA00228 -> CA00266
(proposed reaction: CA00190 -> CA00255), Proposed reaction (CA00255 -> CA00281)
Necessary enzymes for those reactions in theory:
CrtI (
CR00119
: CA00043 -> CA00042) --> AL2 (
CR00370
: CA00042 -> CA00190) --> unknown (CA00190 -> CA00255) --> unknown (CA00255 -> CA00281)
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CA00280 (4,4'-Diketo-γ-carotene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00256
(4-Keto-γ-carotene)
->
CA00280
(4,4'-Diketo-γ-carotene)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000138
(Knwon path in Myxococcus (bacterium): CA00191 -> CA00256), Proposed reaction (CA00256 -> CA00280)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> unknown (CA00191 -> CA00256) --> unknown (CA00256 -> CA00280)
☀
CA00271 (1',2'-Dihydroxy-4-ketotorulene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00042
(3,4-Dehydrolycopene)
->
CA00190
(Torulene)
->
CA00217
(1'-Hydroxytorulene)
->
CA00206
(Plectaniaxanthin)
->
CA00271
(1',2'-Dihydroxy-4-ketotorulene)
See:
CB000077
(Knwon path in mold: CA00043 -> CA00042),
CB000078
(Knwon path in mold: CA00042 -> CA00190), similar to
CB000024: CA00191 -> CA00202
(proposed reaction: CA00190 -> CA00217), (CA00217 -> CA00206), similar to
CB000026: CA00228 -> CA00266
(proposed reaction: CA00206 -> CA00271)
Necessary enzymes for those reactions in theory:
CrtI (
CR00119
: CA00043 -> CA00042) --> AL2 (
CR00370
: CA00042 -> CA00190) --> unknown (CA00190 -> CA00217) --> unknown (CA00217 -> CA00206) --> unknown (CA00206 -> CA00271)
Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428
Since June 15th, 2015 by Junko Yabuzaki.
