Carotenoids obi
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                            (Land plant: common tobacco)
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☀ Pathway reconstructed carotenoids:       Search similar carotenogenesis pathway constructing organisms  ]  
  1. CA01165 (Oxoedulan)
  2. CA01171 (Megastigma-5,8-dien-4-one)
  3. CA01172 (4-oxo-β-ionone)
  4. CA01170 (Megastigma-4,6,8-trien-3-one)
  5. CA01169 (Megastigma-4,7E,9-trien-3-one)
  6. CA01164 (Vitispirane)
  7. CA00802 (γ-Damascenone)
☀ Pathway unconstructed carotenoids: CA01165 (Oxoedulan), CA01171 (Megastigma-5,8-dien-4-one), CA01170 (Megastigma-4,6,8-trien-3-one), CA01169 (Megastigma-4,7E,9-trien-3-one), CA01164 (Vitispirane), CA00802 (γ-Damascenone)
☀ Lycopene biosynthesis type: Plant type (Ref.690)


  ☀ CA00043 (Lycopene) biosynthesis pathway

   Path: CA00189 (Prephytoene pyrophosphate (diphosphate)) -> CA00060 (Phytoene) -> CA00059 ((9Z,15Z)-Phytofluene) -> CA00053 ((9Z,15Z,9'Z)-ζ-Carotene) -> CA00065 ((9Z,9'Z)-ζ-Carotene) -> CA00066 ((7Z,9Z,9'Z)-Neurosporene) -> CA00044 (Prolycopene) -> CA00043 (Lycopene)

   See: CB000004 (Cyanobacterial and higher plant pathay: CA00189 -> CA00060 -> CA00059 -> CA00053 -> CA00065 -> CA00066 -> CA00044 -> CA00043)

   Necessary enzymes for those reactions in theory: CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (CR00277: CA00189 -> CA00060) --> PDS(1.3.5.5) (CR00015: CA00060 -> CA00059) --> PDS(1.3.5.5) (CR00016: CA00059 -> CA00053) --> Z-ISO(5.2.1.12) (CR00390: CA00053 -> CA00065) --> CrtI(1.3.5.6), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00011: CA00065 -> CA00066) --> CrtI(1.3.5.6), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00012: CA00066 -> CA00044) --> CRTISO(5.2.1.13) (CR00391: CA00044 -> CA00043)




  ☀ CA01172 (4-oxo-β-ionone) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00311 ((9Z)-β-Carotene) -> CA00803 (β-Ionone) -> CA01172 (4-oxo-β-ionone)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000079 (Knwon path in Arabidopsis sp.: CA00309 -> CA00311), CB000086 (Knwon path in general: CA00311 -> CA00803), Proposed reaction (CA00803 -> CA01172)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> DWARF27 (CR00357: CA00309 -> CA00311) --> CCD7, MAX3, D17/HTD1, RMS5, DAD1, NCED7 (CR00082: CA00311 -> CA00803) --> unknown (CA00803 -> CA01172)




Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428

Since June 15th, 2015 by Junko Yabuzaki.