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☀ Pathway reconstructed carotenoids:       [  Search similar carotenogenesis pathway constructing organisms  ]  

1. CA00060 (Phytoene)
   
2. CA00191 (γ-Carotene)
   
3. CA00190 (Torulene)
   
4. CA00283 (Torularhodin)
   
5. CA00309 (β-Carotene)

☀ Pathway unconstructed carotenoids: None
☀ Lycopene biosynthesis type: Bacterial type (Ref.690)

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  ☀ CA00043 (Lycopene) biosynthesis pathway

   Path: CA00189 (Prephytoene pyrophosphate (diphosphate)) -> CA00060 (Phytoene) -> CA00058 ((all-E)-Phytofluene) -> CA00051 (ζ-Carotene) -> CA00047 (Neurosporene) -> CA00043 (Lycopene)

   See: CB000005 (Bacterial and fungal pathway: CA00189 -> CA00060 -> CA00058 -> CA00051 -> CA00047 -> CA00043)

   Necessary enzymes for those reactions in theory: CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (CR00277: CA00189 -> CA00060) --> Crtlb(1.3.99.28), CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.99.29), Crtla(1.3.99.29) (CR00389: CA00060 -> CA00058) --> CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.5.5, 1.3.99.29), Crtla(1.3.99.29) (CR00115: CA00058 -> CA00051) --> PDS(1.3.5.5, 1.3.99.29), CitPDS1(1.3.5.5), BoPDS(1.3.5.5), CrtI(1.3.5.6, 1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00136: CA00051 -> CA00047) --> CrtI(1.3.5.6, 1.3.99.30, 1.3.99.31), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6), Crtlb(1.3.99.26) (CR00132: CA00047 -> CA00043)




  ☀ CA00190 (Torulene) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00042 (3,4-Dehydrolycopene) -> CA00190 (Torulene)

   See: CB000078 (Knwon path in mold: CA00043 -> CA00042 -> CA00190)

   Necessary enzymes for those reactions in theory: CrtI (CR00119: CA00043 -> CA00042) --> AL2 (CR00370: CA00042 -> CA00190)




  ☀ CA00283 (Torularhodin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00190 (Torulene) -> CA00283 (Torularhodin)

   See: CB000144 (CA00043 -> CA00191 -> CA00190 -> CA00283)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtI (CR00114: CA00191 -> CA00190) --> unknown (CA00190 -> CA00283)




  ☀ CA00309 (β-Carotene) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene)

   See: CB000081 (Knwon path in general: CA00043 -> CA00191 -> CA00309)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309)

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Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428

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Since June 15th, 2015 by Junko Yabuzaki.