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CarotenoidsDB:
Thermus thermophilus
carotenoids (Bacterial) reconstructed pathways in theory
   
(Deinococcus-Thermus: Thermophilic bacterium)
   
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Click here to see the carotenoid profile of Thermus thermophilus
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Pathway reconstructed carotenoids:
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CA00043 (Lycopene)
CA00060 (Phytoene)
CA00309 (β-Carotene)
CA00322 (β-Cryptoxanthin)
CA00328 (Zeaxanthin)
CA00383 (Thermocryptoxanthin-11)
CA00384 (Zeaxanthin diglucoside)
CA00385 (Thermocryptoxanthin-13)
CA00386 (Thermozeaxanthin-13)
CA00387 (Thermocryptoxanthin-15)
CA00388 (Thermozeaxanthin-15)
CA00389 (Thermozeaxanthin-17)
CA00391 (Thermobiszeaxanthin-13-13)
CA00392 (Thermobiszeaxanthin-13-15)
CA00393 (Thermobiszeaxanthin-15-15)
☀
Pathway unconstructed carotenoids:
None
☀
Lycopene biosynthesis type:
Bacterial type (Ref.690)
☀
CA00043 (Lycopene)
biosynthesis pathway
Path:
CA00189
(Prephytoene pyrophosphate (diphosphate))
->
CA00060
(Phytoene)
->
CA00058
((all-E)-Phytofluene)
->
CA00051
(ζ-Carotene)
->
CA00047
(Neurosporene)
->
CA00043
(Lycopene)
See:
CB000005
(Bacterial and fungal pathway: CA00189 -> CA00060 -> CA00058 -> CA00051 -> CA00047 -> CA00043)
Necessary enzymes for those reactions in theory:
CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (
CR00277
: CA00189 -> CA00060) --> Crtlb(1.3.99.28), CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.99.29), Crtla(1.3.99.29) (
CR00389
: CA00060 -> CA00058) --> CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.5.5, 1.3.99.29), Crtla(1.3.99.29) (
CR00115
: CA00058 -> CA00051) --> PDS(1.3.5.5, 1.3.99.29), CitPDS1(1.3.5.5), BoPDS(1.3.5.5), CrtI(1.3.5.6, 1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (
CR00136
: CA00051 -> CA00047) --> CrtI(1.3.5.6, 1.3.99.30, 1.3.99.31), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6), Crtlb(1.3.99.26) (
CR00132
: CA00047 -> CA00043)
☀
CA00383 (Thermocryptoxanthin-11)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00383
(Thermocryptoxanthin-11)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CR00312
(CA00322 -> CA00383)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (
CR00312
: CA00322 -> CA00383)
☀
CA00384 (Zeaxanthin diglucoside)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00328
(Zeaxanthin)
->
CA00384
(Zeaxanthin diglucoside)
See:
CB000028
(Knwon path in general: CA00043 -> CA00191 -> CA00309 -> CA00322 -> CA00328 -> CA00384)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00190
: CA00322 -> CA00328) --> CrtX (
CR00299
: CA00328 -> CA00384)
☀
CA00387 (Thermocryptoxanthin-15)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00387
(Thermocryptoxanthin-15)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CR00314
(CA00322 -> CA00387)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (
CR00314
: CA00322 -> CA00387)
☀
CA00388 (Thermozeaxanthin-15)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00387
(Thermocryptoxanthin-15)
->
CA00388
(Thermozeaxanthin-15)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CR00314
(CA00322 -> CA00387),
CR00189
(CA00387 -> CA00388)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (
CR00314
: CA00322 -> CA00387) --> unknown (
CR00189
: CA00387 -> CA00388)
☀
CA00389 (Thermozeaxanthin-17)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00328
(Zeaxanthin)
->
CA00389
(Thermozeaxanthin-17)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CB000028
(Knwon path in general: CA00322 -> CA00328), Proposed reaction (CA00328 -> CA00389)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00190
: CA00322 -> CA00328) --> unknown (CA00328 -> CA00389)
☀
CA00391 (Thermobiszeaxanthin-13-13)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00385
(Thermocryptoxanthin-13)
->
CA00386
(Thermozeaxanthin-13)
->
CA00391
(Thermobiszeaxanthin-13-13)
See:
CB000029
(Knwon path in Thermus thermophilus: CA00043 -> CA00191 -> CA00309 -> CA00322 -> CA00385 -> CA00386 -> CA00391)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (
CR00313
: CA00322 -> CA00385) --> unknown (
CR00188
: CA00385 -> CA00386) --> unknown (
CR00315
: CA00386 -> CA00391)
☀
CA00392 (Thermobiszeaxanthin-13-15)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00385
(Thermocryptoxanthin-13)
->
CA00386
(Thermozeaxanthin-13)
->
CA00392
(Thermobiszeaxanthin-13-15)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CB000029
(Knwon path in Thermus thermophilus: CA00322 -> CA00385),
CB000029
(Knwon path in Thermus thermophilus: CA00385 -> CA00386),
CR00280
(CA00386 -> CA00392)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (
CR00313
: CA00322 -> CA00385) --> unknown (
CR00188
: CA00385 -> CA00386) --> unknown (
CR00280
: CA00386 -> CA00392)
☀
CA00393 (Thermobiszeaxanthin-15-15)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00387
(Thermocryptoxanthin-15)
->
CA00388
(Thermozeaxanthin-15)
->
CA00393
(Thermobiszeaxanthin-15-15)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CR00314
(CA00322 -> CA00387),
CR00189
(CA00387 -> CA00388),
CR00316
(CA00388 -> CA00393)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (
CR00314
: CA00322 -> CA00387) --> unknown (
CR00189
: CA00387 -> CA00388) --> unknown (
CR00316
: CA00388 -> CA00393)
Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428
Since June 15th, 2015 by Junko Yabuzaki.