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☀ Pathway reconstructed carotenoids:       [  Search similar carotenogenesis pathway constructing organisms  ]  
  1. CA00230 (Myxol 2'-rhamnoside)
  2. CA00309 (β-Carotene)
  3. CA00322 (β-Cryptoxanthin)
  4. CA00328 (Zeaxanthin)
  5. CA00397 (Mutatochrome)
  6. CA00462 (Echinenone)
  7. CA00471 (Canthaxanthin)
☀ Pathway unconstructed carotenoids: None
☀ Lycopene biosynthesis type: Plant type (Ref.690)

  ☀ CA00043 (Lycopene) biosynthesis pathway

   Path: CA00189 (Prephytoene pyrophosphate (diphosphate)) -> CA00060 (Phytoene) -> CA00059 ((9Z,15Z)-Phytofluene) -> CA00053 ((9Z,15Z,9'Z)-ζ-Carotene) -> CA00065 ((9Z,9'Z)-ζ-Carotene) -> CA00066 ((7Z,9Z,9'Z)-Neurosporene) -> CA00044 (Prolycopene) -> CA00043 (Lycopene)

   See: CB000004 (Cyanobacterial and higher plant pathay: CA00189 -> CA00060 -> CA00059 -> CA00053 -> CA00065 -> CA00066 -> CA00044 -> CA00043)

   Necessary enzymes for those reactions in theory: CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (CR00277: CA00189 -> CA00060) --> PDS(1.3.5.5) (CR00015: CA00060 -> CA00059) --> PDS(1.3.5.5) (CR00016: CA00059 -> CA00053) --> Z-ISO(5.2.1.12) (CR00390: CA00053 -> CA00065) --> CrtI(1.3.5.6), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00011: CA00065 -> CA00066) --> CrtI(1.3.5.6), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00012: CA00066 -> CA00044) --> CRTISO(5.2.1.13) (CR00391: CA00044 -> CA00043)




  ☀ CA00230 (Myxol 2'-rhamnoside) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00228 (Myxol) -> CA00230 (Myxol 2'-rhamnoside)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000026 (Knwon path in Anabaena (cyanobacterium): CA00191 -> CA00228), Proposed reaction (CA00228 -> CA00230)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> unknown (CA00191 -> CA00228) --> unknown (CA00228 -> CA00230)




  ☀ CA00328 (Zeaxanthin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00322 (β-Cryptoxanthin) -> CA00328 (Zeaxanthin)

   See: CB000081 (Knwon path in general: CA00043 -> CA00191 -> CA00309 -> CA00322 -> CA00328)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (CR00192: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (CR00190: CA00322 -> CA00328)




  ☀ CA00397 (Mutatochrome) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00396 (β-Carotene 5,6-epoxide) -> CA00397 (Mutatochrome)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CR00157 (CA00309 -> CA00396), CR00162 (CA00396 -> CA00397)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> unknown (CR00157: CA00309 -> CA00396) --> unknown (CR00162: CA00396 -> CA00397)




  ☀ CA00471 (Canthaxanthin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00462 (Echinenone) -> CA00471 (Canthaxanthin)

   See: CB000056 (Knwon path in general: CA00043 -> CA00191 -> CA00309 -> CA00462 -> CA00471)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtO, CrtW (CR00234: CA00309 -> CA00462) --> CrtO, CrtW (CR00241: CA00462 -> CA00471)



Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428
Since June 15th, 2015 by Junko Yabuzaki.