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CarotenoidsDB:
Epicoccum nigrum
carotenoids (Eukaryote) reconstructed pathways in theory
   
(Fungi: fungus, a plant pathogen)
   
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Click here to see the carotenoid profile of Epicoccum nigrum
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Pathway reconstructed carotenoids:
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CA00283 (Torularhodin)
CA00319 (3,4,3',4'-Bisdehydro-β-carotene)
CA00315 (3,4-Didehydro-β-carotene)
CA00321 (2-Hydroxy-β-carotene)
CA00466 (Rhodoxanthin)
☀
Pathway unconstructed carotenoids:
None
☀
Lycopene biosynthesis type:
Bacterial type (Ref.690)
☀
CA00043 (Lycopene)
biosynthesis pathway
Path:
CA00189
(Prephytoene pyrophosphate (diphosphate))
->
CA00060
(Phytoene)
->
CA00058
((all-E)-Phytofluene)
->
CA00051
(ζ-Carotene)
->
CA00047
(Neurosporene)
->
CA00043
(Lycopene)
See:
CB000005
(Bacterial and fungal pathway: CA00189 -> CA00060 -> CA00058 -> CA00051 -> CA00047 -> CA00043)
Necessary enzymes for those reactions in theory:
CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (
CR00277
: CA00189 -> CA00060) --> Crtlb(1.3.99.28), CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.99.29), Crtla(1.3.99.29) (
CR00389
: CA00060 -> CA00058) --> CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.5.5, 1.3.99.29), Crtla(1.3.99.29) (
CR00115
: CA00058 -> CA00051) --> PDS(1.3.5.5, 1.3.99.29), CitPDS1(1.3.5.5), BoPDS(1.3.5.5), CrtI(1.3.5.6, 1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (
CR00136
: CA00051 -> CA00047) --> CrtI(1.3.5.6, 1.3.99.30, 1.3.99.31), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6), Crtlb(1.3.99.26) (
CR00132
: CA00047 -> CA00043)
☀
CA00283 (Torularhodin)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00190
(Torulene)
->
CA00283
(Torularhodin)
See:
CB000144
(CA00043 -> CA00191 -> CA00190 -> CA00283)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtI (
CR00114
: CA00191 -> CA00190) --> unknown (CA00190 -> CA00283)
☀
CA00319 (3,4,3',4'-Bisdehydro-β-carotene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00328
(Zeaxanthin)
->
CA00384
(Zeaxanthin diglucoside)
->
CA00319
(3,4,3',4'-Bisdehydro-β-carotene)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CB000028
(Knwon path in general: CA00322 -> CA00328),
CB000028
(Knwon path in general: CA00328 -> CA00384), Proposed reaction (CA00384 -> CA00319)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00190
: CA00322 -> CA00328) --> CrtX (
CR00299
: CA00328 -> CA00384) --> unknown (CA00384 -> CA00319)
☀
CA00315 (3,4-Didehydro-β-carotene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00360
(Cryptoxanthin glucoside)
->
CA00315
(3,4-Didehydro-β-carotene)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322), (CA00322 -> CA00360), (CA00360 -> CA00315)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> unknown (CA00322 -> CA00360) --> unknown (CA00360 -> CA00315)
☀
CA00321 (2-Hydroxy-β-carotene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00321
(2-Hydroxy-β-carotene)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309), Proposed reaction (CA00309 -> CA00321)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> unknown (CA00309 -> CA00321)
☀
CA00466 (Rhodoxanthin)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00328
(Zeaxanthin)
->
CA01098
(3,3'-Diketo-ε-carotene)
->
CA01208
(Piprixanthin)
->
CA00466
(Rhodoxanthin)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CB000028
(Knwon path in general: CA00322 -> CA00328),
CB000107
(Knwon path in birds: CA00328 -> CA01098),
CB000107
(Knwon path in birds: CA01098 -> CA01208),
CB000107
(Knwon path in birds: CA01208 -> CA00466)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00190
: CA00322 -> CA00328) --> unknown (CA00328 -> CA01098) --> unknown (CA01098 -> CA01208) --> unknown (CA01208 -> CA00466)
Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428
Since June 15th, 2015 by Junko Yabuzaki.