Carotenoids obi
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                            (Alphaproteobacteria: root nodule bacterium)
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☀ Pathway reconstructed carotenoids:       [  Search similar carotenogenesis pathway constructing organisms  ]  
  1. CA00016 (4,4'-Diaplycopene-4,4'-dioic acid)
  2. CA00309 (β-Carotene)
  3. CA00326 (2,3-Dihydroxy-β-carotene)
  4. CA00394 (2,3,2'-Trihydroxy-β-carotene)
  5. CA00462 (Echinenone)
  6. CA00471 (Canthaxanthin)
  7. CA00479 ()
  8. CA00487 (Adonirubin)
  9. CA01052 ((2R,3S)-2,3-Dihydroxy-β-carotene-4-one)
  10. CA00499 (2-Hydroxyadonirubin)
  11. CA00511 (4-Ketonostoxanthin)
☀ Pathway unconstructed carotenoids: None
☀ Lycopene biosynthesis type: Bacterial type (Diapolycopene)

  ☀ CA00001 (4,4'-Diapolycopene) biosynthesis pathway

   Path: CA00008 (4,4'-Diapophytoene) -> CA00007 (4,4'-Diapophytofluene) -> CA00006 (4,4'-Diapo-ζ-carotene) -> CA00002 (4,4'-Diaponeurosporene) -> CA00001 (4,4'-Diapolycopene)

   See: CB000001 (Knwon path in bacterium: CA00008 -> CA00007 -> CA00006 -> CA00002 -> CA00001)

   Necessary enzymes for those reactions in theory: unknown (CR00272: CA00008 -> CA00007) --> unknown (CR00116: CA00007 -> CA00006) --> unknown (CR00133: CA00006 -> CA00002) --> CrtN(1.3.8.2) (CR00137: CA00002 -> CA00001)




  ☀ CA00016 (4,4'-Diaplycopene-4,4'-dioic acid) biosynthesis pathway

   Path: CA00008 (4,4'-Diapophytoene) -> CA00001 (4,4'-Diapolycopene) -> CA00010 (4,4'-Diapolycopen-4-al) -> CA00013 (4,4'-Diapolycopenedial) -> CA00016 (4,4'-Diaplycopene-4,4'-dioic acid)

   See: CB000102 (Knwon path in Halobacillus: CA00008 -> CA00001), CR00005 (CA00001 -> CA00010), CR00008 (CA00010 -> CA00013), CR00224 (CA00013 -> CA00016)

   Necessary enzymes for those reactions in theory: CrtN (CR00013: CA00008 -> CA00001) --> CrtOx (CR00005: CA00001 -> CA00010) --> CrtOx (CR00008: CA00010 -> CA00013) --> Ald (CR00224: CA00013 -> CA00016)




  ☀ CA00043 (Lycopene) biosynthesis pathway

   Path: CA00189 (Prephytoene pyrophosphate (diphosphate)) -> CA00060 (Phytoene) -> CA00058 ((all-E)-Phytofluene) -> CA00051 (ζ-Carotene) -> CA00047 (Neurosporene) -> CA00043 (Lycopene)

   See: CB000005 (Bacterial and fungal pathway: CA00189 -> CA00060 -> CA00058 -> CA00051 -> CA00047 -> CA00043)

   Necessary enzymes for those reactions in theory: CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (CR00277: CA00189 -> CA00060) --> Crtlb(1.3.99.28), CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.99.29), Crtla(1.3.99.29) (CR00389: CA00060 -> CA00058) --> CrtI(1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), PDS(1.3.5.5, 1.3.99.29), Crtla(1.3.99.29) (CR00115: CA00058 -> CA00051) --> PDS(1.3.5.5, 1.3.99.29), CitPDS1(1.3.5.5), BoPDS(1.3.5.5), CrtI(1.3.5.6, 1.3.99.28, 1.3.99.30, 1.3.99.31), Crtlb(1.3.99.28), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (CR00136: CA00051 -> CA00047) --> CrtI(1.3.5.6, 1.3.99.30, 1.3.99.31), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6), Crtlb(1.3.99.26) (CR00132: CA00047 -> CA00043)




  ☀ CA00326 (2,3-Dihydroxy-β-carotene) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00322 (β-Cryptoxanthin) -> CA00326 (2,3-Dihydroxy-β-carotene)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000028 (Knwon path in general: CA00309 -> CA00322), similar to CB000030: CA00328 -> CA00338 (proposed reaction: CA00322 -> CA00326)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (CR00192: CA00309 -> CA00322) --> unknown (CA00322 -> CA00326)




  ☀ CA00394 (2,3,2'-Trihydroxy-β-carotene) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00322 (β-Cryptoxanthin) -> CA00326 (2,3-Dihydroxy-β-carotene) -> CA00394 (2,3,2'-Trihydroxy-β-carotene)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000028 (Knwon path in general: CA00309 -> CA00322), similar to CB000030: CA00328 -> CA00338 (proposed reaction: CA00322 -> CA00326), similar to CB000030: CA00338 -> CA00346 (proposed reaction: CA00326 -> CA00394)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (CR00192: CA00309 -> CA00322) --> unknown (CA00322 -> CA00326) --> unknown (CA00326 -> CA00394)




  ☀ CA00479 () biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00322 (β-Cryptoxanthin) -> CA00479 ()

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000028 (Knwon path in general: CA00309 -> CA00322), CR00235 (CA00322 -> CA00479)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (CR00192: CA00309 -> CA00322) --> CrtW (CR00235: CA00322 -> CA00479)




  ☀ CA00487 (Adonirubin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00462 (Echinenone) -> CA00471 (Canthaxanthin) -> CA00487 (Adonirubin)

   See: CB000056 (Knwon path in general: CA00043 -> CA00191 -> CA00309 -> CA00462 -> CA00471 -> CA00487)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtO, CrtW (CR00234: CA00309 -> CA00462) --> CrtO, CrtW (CR00241: CA00462 -> CA00471) --> CrtZ (CR00185: CA00471 -> CA00487)




  ☀ CA01052 ((2R,3S)-2,3-Dihydroxy-β-carotene-4-one) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00462 (Echinenone) -> CA00479 () -> CA01052 ((2R,3S)-2,3-Dihydroxy-β-carotene-4-one)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000055 (Knwon path in Gordonia (bacterium): CA00309 -> CA00462), CR00183 (CA00462 -> CA00479), similar to CB000030: CA00328 -> CA00338 (proposed reaction: CA00479 -> CA01052)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtO, CrtW (CR00234: CA00309 -> CA00462) --> CrtZ (CR00183: CA00462 -> CA00479) --> unknown (CA00479 -> CA01052)




  ☀ CA00499 (2-Hydroxyadonirubin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00462 (Echinenone) -> CA00471 (Canthaxanthin) -> CA00487 (Adonirubin) -> CA00499 (2-Hydroxyadonirubin)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000055 (Knwon path in Gordonia (bacterium): CA00309 -> CA00462), CB000055 (Knwon path in Gordonia (bacterium): CA00462 -> CA00471), CB000056 (Knwon path in general: CA00471 -> CA00487), similar to CB000030: CA00328 -> CA00338 (proposed reaction: CA00487 -> CA00499)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtO, CrtW (CR00234: CA00309 -> CA00462) --> CrtO, CrtW (CR00241: CA00462 -> CA00471) --> CrtZ (CR00185: CA00471 -> CA00487) --> unknown (CA00487 -> CA00499)




  ☀ CA00511 (4-Ketonostoxanthin) biosynthesis pathway

   Path: CA00043 (Lycopene) -> CA00191 (γ-Carotene) -> CA00309 (β-Carotene) -> CA00462 (Echinenone) -> CA00479 () -> CA01052 ((2R,3S)-2,3-Dihydroxy-β-carotene-4-one) -> CA00506 (2-Hydroxyadonixanthin) -> CA00511 (4-Ketonostoxanthin)

   See: CB000007 (Knwon path in general: CA00043 -> CA00191), CB000009 (Knwon path in general: CA00191 -> CA00309), CB000055 (Knwon path in Gordonia (bacterium): CA00309 -> CA00462), CR00183 (CA00462 -> CA00479), similar to CB000030: CA00328 -> CA00338 (proposed reaction: CA00479 -> CA01052), similar to CB000028: CA00322 -> CA00328 (proposed reaction: CA01052 -> CA00506), similar to CB000030: CA00338 -> CA00346 (proposed reaction: CA00506 -> CA00511)

   Necessary enzymes for those reactions in theory: CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (CR00374: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (CR00365: CA00191 -> CA00309) --> CrtO, CrtW (CR00234: CA00309 -> CA00462) --> CrtZ (CR00183: CA00462 -> CA00479) --> unknown (CA00479 -> CA01052) --> unknown (CA01052 -> CA00506) --> unknown (CA00506 -> CA00511)



Since June 15th, 2015 by Junko Yabuzaki.