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CarotenoidsDB:
Isochrysis galbana
carotenoids (Eukaryote) reconstructed pathways in theory
   
(Alga: Haptophyte)
   
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Click here to see the carotenoid profile of Isochrysis galbana
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Pathway reconstructed carotenoids:
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CA00309 (β-Carotene)
CA00324 (Diatoxanthin)
CA00404 (Diadinoxanthin)
CA00462 (Echinenone)
CA00519 (Fucoxanthin)
CA00587 (α-Carotene)
☀
Pathway unconstructed carotenoids:
None
☀
Lycopene biosynthesis type:
Plant type (Ref.690)
☀
CA00043 (Lycopene)
biosynthesis pathway
Path:
CA00189
(Prephytoene pyrophosphate (diphosphate))
->
CA00060
(Phytoene)
->
CA00059
((9Z,15Z)-Phytofluene)
->
CA00053
((9Z,15Z,9'Z)-ζ-Carotene)
->
CA00065
((9Z,9'Z)-ζ-Carotene)
->
CA00066
((7Z,9Z,9'Z)-Neurosporene)
->
CA00044
(Prolycopene)
->
CA00043
(Lycopene)
See:
CB000004
(Cyanobacterial and higher plant pathay: CA00189 -> CA00060 -> CA00059 -> CA00053 -> CA00065 -> CA00066 -> CA00044 -> CA00043)
Necessary enzymes for those reactions in theory:
CrtB(2.5.1.32), CitPsy(2.5.1.32), AtPSY(2.5.1.32) (
CR00277
: CA00189 -> CA00060) --> PDS(1.3.5.5) (
CR00015
: CA00060 -> CA00059) --> PDS(1.3.5.5) (
CR00016
: CA00059 -> CA00053) --> Z-ISO(5.2.1.12) (
CR00390
: CA00053 -> CA00065) --> CrtI(1.3.5.6), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (
CR00011
: CA00065 -> CA00066) --> CrtI(1.3.5.6), CrtQa(1.3.5.6), CrtQb(1.3.5.6), ZDS(1.3.5.6) (
CR00012
: CA00066 -> CA00044) --> CRTISO(5.2.1.13) (
CR00391
: CA00044 -> CA00043)
☀
CA00324 (Diatoxanthin)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00328
(Zeaxanthin)
->
CA00407
(Antheraxanthin)
->
CA00416
(Violaxanthin)
->
CA00414
(Neoxanthin)
->
CA00404
(Diadinoxanthin)
->
CA00324
(Diatoxanthin)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CB000028
(Knwon path in general: CA00322 -> CA00328),
CB000038
(Algal and higher plant pathway (probably eukaryotic): CA00328 -> CA00407),
CB000038
(Algal and higher plant pathway (probably eukaryotic): CA00407 -> CA00416),
CB000040
(Knwon path in general: CA00416 -> CA00414),
CB000042
(Knwon path in Phaeodactylum: CA00414 -> CA00404),
CB000037
(Knwon path in Chromophyta algae: CA00404 -> CA00324)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00190
: CA00322 -> CA00328) --> ZEP(1.14.13.90) (
CR00158
: CA00328 -> CA00407) --> ZEP(1.14.13.90) (
CR00159
: CA00407 -> CA00416) --> ABA4(5.3.99.9), NSY(5.3.99.9), NXS(5.3.99.9) (
CR00382
: CA00416 -> CA00414) --> unknown (
CR00141
: CA00414 -> CA00404) --> VDE, VDL1, VDL2 (
CR00395
: CA00404 -> CA00324)
☀
CA00462 (Echinenone)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00462
(Echinenone)
See:
CB000062
(Knwon path in general: CA00043 -> CA00191 -> CA00309 -> CA00462)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtO, CrtW (
CR00234
: CA00309 -> CA00462)
☀
CA00519 (Fucoxanthin)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00191
(γ-Carotene)
->
CA00309
(β-Carotene)
->
CA00322
(β-Cryptoxanthin)
->
CA00328
(Zeaxanthin)
->
CA00407
(Antheraxanthin)
->
CA00416
(Violaxanthin)
->
CA00414
(Neoxanthin)
->
CA00519
(Fucoxanthin)
See:
CB000007
(Knwon path in general: CA00043 -> CA00191),
CB000009
(Knwon path in general: CA00191 -> CA00309),
CB000028
(Knwon path in general: CA00309 -> CA00322),
CB000028
(Knwon path in general: CA00322 -> CA00328),
CB000038
(Algal and higher plant pathway (probably eukaryotic): CA00328 -> CA00407),
CB000038
(Algal and higher plant pathway (probably eukaryotic): CA00407 -> CA00416),
CB000040
(Knwon path in general: CA00416 -> CA00414),
CB000064
(Knwon path in Phaeodactylum (algae): CA00414 -> CA00519)
Necessary enzymes for those reactions in theory:
CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P(5.5.1.19), AL2(5.5.1.19) (
CR00374
: CA00043 -> CA00191) --> CrtL(5.5.1.19), CrtY(5.5.1.19), CrtL-b(5.5.1.19), CruA/P, AL2, PSY(2.5.1.32) (
CR00365
: CA00191 -> CA00309) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00192
: CA00309 -> CA00322) --> CrtR(1.14.13.129), CrtZ(1.14.13.129), LUT5(1.14.13.129), BCH(1.14.13.129) (
CR00190
: CA00322 -> CA00328) --> ZEP(1.14.13.90) (
CR00158
: CA00328 -> CA00407) --> ZEP(1.14.13.90) (
CR00159
: CA00407 -> CA00416) --> ABA4(5.3.99.9), NSY(5.3.99.9), NXS(5.3.99.9) (
CR00382
: CA00416 -> CA00414) --> unknown (
CR00291
: CA00414 -> CA00519)
☀
CA00587 (α-Carotene)
biosynthesis pathway
Path:
CA00043
(Lycopene)
->
CA00298
(δ-Carotene)
->
CA00587
(α-Carotene)
See:
CB000034
(Knwon path in general: CA00043 -> CA00298 -> CA00587)
Necessary enzymes for those reactions in theory:
CrtL-e(5.5.1.18), LCYe(5.5.1.18) (
CR00377
: CA00043 -> CA00298) --> LCYb, CrtL(5.5.1.19), CrtL-b(5.5.1.19), CrtL-e(5.5.1.19) (
CR00367
: CA00298 -> CA00587)
Ref.690 : Enfissi EM, Nogueira M, Bramley PM, Fraser PD, Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7., "The regulation of carotenoid formation in tomato fruit.", PMID: 27865019 DOI: 10.1111/tpj.13428
Since June 15th, 2015 by Junko Yabuzaki.